Shows

They've shared the results with the U.S. National Institutes of Health, which publishes treatment guidelines, and they hope for a World Health Organization recommendation.

“If WHO recommends this, you will see it widely taken up,” said study co-author Dr. Edward Mills of McMaster University in Hamilton, Ontario, adding that many poor nations have the drug readily available. “We hope it will lead to a lot of lives saved.”

The pill, called fluvoxamine, would cost $4 for a course of COVID-19 treatment. By comparison, antibody IV treatments cost about $2,000 and Merck's experimental antiviral pill for COVID-19 is about $700 per course. Some experts predict various treatments eventually will be used in combination to fight the coronavirus.

Researchers tested the antidepressant in nearly 1,500 Brazilians recently infected with coronavirus who were at risk of severe illness because of other health problems, such as diabetes. About half took the antidepressant at home for 10 days, the rest got dummy pills. They were tracked for four weeks to see who landed in the hospital or spent extended time in an emergency room when hospitals were full.

In the group that took the drug, 11% needed hospitalization or an extended ER stay, compared to 16% of those on dummy pills.

The results, published Wednesday in the journal Lancet Global Health, were so strong that independent experts monitoring the study recommended stopping it early because the results were clear.

aside">> Top Picks In Shopping

Questions remain about the best dosing, whether lower risk patients might also benefit and whether the pill should be combined with other treatments.

The larger project looked at eight existing drugs to see if they could work against the pandemic virus. The project is still testing a hepatitis drug, but all the others — including metformin, hydroxychloroquine and ivermectin — haven't panned out.

The cheap generic and Merck's COVID-19 pill work in different ways and “may be complementary,” said Dr. Paul Sax of Brigham and Women’s Hospital and Harvard Medical School, who was not involved in the study. Earlier this month, Merck asked regulators in the U.S. and Europe to authorize its antiviral pill.

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

Source : https://www.sfgate.com/news/article/Cheap-antidepressant-shows-promise-treating-early-16569733.php

1051
Cheap antidepressant shows promise treating early COVID-19

Source:SFGate

Cheap antidepressant shows promise treating early COVID-19

Most Americans say climate change is a crisis, new study shows

Source:CBS News

Most Americans say climate change is a crisis, new study shows

Fact check: Image shows NASAs flying observatory and an internet balloon

Source:YAHOO!News

Fact check: Image shows NASAs flying observatory and an internet balloon

Some fast-food items contain plastics linked to serious health problems, new report shows

Source:Washington Post

Some fast-food items contain plastics linked to serious health problems, new report shows

Early tally shows Anchorage Assembly member surviving recall

Source:SFGate

Early tally shows Anchorage Assembly member surviving recall

Labor has led Coalition in eight of nine Guardian Essential polls, analysis shows

Source:The Guardian

Labor has led Coalition in eight of nine Guardian Essential polls, analysis shows