New England Patriots Vs. Buffalo Bills Picks, Predictions: Who Wins NFL Week 13 Game?

One AFC East team will advance to next week's Divisional Round of the 2022 NFL playoffs, and the other will go home until next year when the Buffalo Bills and New England Patriots collide for the third time this season in a Super Wild Card Weekend game on Saturday night at Highmark Stadium in Orchard Park, N.Y. The teams split the earlier two matchups; the Patriots (10-7) won in Week 13 in Buffalo, while the Bills (11-6) prevailed in Week 16 in Foxborough, Mass. But Saturday's game will be just the second postseason matchup between the teams. In the AFL Divisional Round in 1963, the Patriots defeated the Bills 26-8. 

Kickoff is set for 8:15 p.m. ET on CBS. Buffalo is a five-point favorite in the latest Bills vs. Patriots odds from Caesars Sportsbook while the over-under for total points scored is 43. Before making any Patriots vs. Bills picks or NFL playoff predictions, you need to see the Wild Card picks from legendary handicapper Hammerin' Hank Goldberg at SportsLine

A beloved national treasure, Goldberg enjoyed 15 winning seasons in his 17-year ESPN run. In 2017, Hammer competed against 10 top handicappers in the Las Vegas Review-Journal's NFL Challenge and beat them all, finishing 50-29-6 in against-the-spread picks. 

He also has a keen eye for both of these teams, especially Buffalo. He 20-11-2 (+763) in his last 33 against-the-spread picks in games involving the Bills and 18-11 (+571) in his last 29 against-the-spread picks in games involving the Patriots. Anyone who has followed him is way up.

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